Saliva Test May Detect Biomarker for Prolonged Concussion

Ricki Lewis, PhD

November 21, 2017

MicroRNAs (miRNAs) may serve as biomarkers of concussion with prolonged symptoms, according to results of a prospective cohort study published online November 20 in JAMA Pediatrics.

More than 80% of concussions follow mild traumatic brain injuries (mTBIs). For one-third of children, symptoms of concussion persist beyond 2 weeks. A tool to predict children at elevated risk for prolonged concussion symptoms (PCS), other than questionnaires to identify clinical risk scores, would be valuable in referring appropriate patients to specialists.

https://www.medscape.com/viewarticle/888983?nlid=119206_4503&src=wnl_dne_171122_mscpedit&uac=178388PR&impID=1490067&faf=1

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Brain Imaging Identifies CTE in a Living Person

New research appears to confirm that positron emission tomography (PET) imaging using the [F-18] FDDNP tracer can identify the distinctive brain tau pathology of chronic traumatic encephalopathy (CTE) in a living person.

The neuropathological findings during a brain autopsy of a retired National Football League (NFL) player confirmed the “fingerprint” signature of CTE uncovered by a previous in vivo [F-18] FDDNP-PET scan

https://www.medscape.com/viewarticle/888817